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CEBPA — PI3

Text-mined interactions from Literome

Cho et al., Hepatology 2003 : The present study was designed to determine whether HGF activates C/EBP in association with the S-phase entrance for cell replication and whether PI3-kinase contributes to the activation of C/EBP ... Whereas stable transfection of the p110 catalytic subunit of PI3-kinase enhanced HGF mediated nuclear translocation of C/EBP beta and DNA binding, stable transfection of p85 subunit or chemical inhibition of PI3-kinase completely blocked C/EBP activation ... In conclusion, HGF induces nuclear translocation of C/EBP beta via the PI3-kinase pathway and stimulates C/EBP DNA binding and gene transcription and that the PI3-kinase mediated C/EBP activation by HGF may contribute to cell replication
Kodama et al., Am J Physiol Cell Physiol 2005 : We found that SNP induced C/EBP homologous protein (CHOP) expression, which inhibited C/EBP binding activity and reduced the C/EBP activity induced by chronic activation of PI3-kinase in a dose dependent manner up to 1.0 mM