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EGR1 — MMP14

Text-mined interactions from Literome

Haas et al., J Biol Chem 1999 : Egr-1 mediates extracellular matrix-driven transcription of membrane type 1 matrix metalloproteinase in endothelium ... These data identify Egr-1 mediated transcription of MT1-MMP as a mechanism by which endothelial cells can initiate an invasive phenotype in response to an alteration in extracellular matrix environment, thus functionally associating MT1-MMP with a growing number of proteins known to be up-regulated by Egr-1 in response to tissue injury or mechanical stress
Yamaguchi et al., Lab Invest 2002 : These results suggest that cyclic strain up-regulates the Egr-1 mediated expression of MT1-MMP in rat microvascular EC, emphasizing the importance of hemodynamic forces in the regulation of MT1-MMP in vivo
Ning et al., Am J Respir Cell Mol Biol 2007 (MAP Kinase Signaling System...) : The identification that induction of MMP-2 and MT1-MMP by CSE from lung fibroblasts is EGR-1 dependent reveals a molecular mechanism for matrix remodeling in cigarette smoke related emphysema
Xiang et al., J Huazhong Univ Sci Technolog Med Sci 2007 : Egr-1 mediates Si0 ( 2 ) -driven transcription of membrane type I matrix metalloproteinase in macrophages
Sanchez-Guerrero et al., PloS one 2012 : Here we show that Egr-1 expression induced by IL-1beta is dependent on metalloproteinases ( MMP ) and a disintegrin and a metalloproteinase ( ADAM ) ... Pharmacologic MMP/ADAM inhibitors and siRNA knockdown prevent IL-1beta induction of Egr-1