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JUN — NOS3

Text-mined interactions from Literome

Kristof et al., J Biol Chem 2001 : Mitogen activated protein kinases mediate activator protein-1 dependent human inducible nitric-oxide synthase promoter activation
Hoffmann et al., J Cell Physiol 2001 : In order to study a potential role of the redox regulated transcription factor complex AP-1 in hypoxia induced eNOS mRNA transcription, c-jun expression was determined and decoy experiments were performed
Kizaki et al., Biochem Biophys Res Commun 2001 : Negative regulation of LPS stimulated expression of inducible nitric oxide synthase by AP-1 in macrophage cell line J774A.1
Lee et al., Life Sci 2003 : The regulation of inducible nitric oxide synthase gene expression induced by lipopolysaccharide and tumor necrosis factor-alpha in C6 cells : involvement of AP-1 and NFkappaB
Rui et al., Cardiovasc Res 2005 (Myocardial Reperfusion Injury) : An AP-1 `` decoy '' oligonucleotide prevented the induction of eNOS by EPO and reversed the beneficial effect of EPO
Cho et al., Biochim Biophys Acta 2005 : BIC also induces nitric oxide synthase in macrophages through JunB/AP-1 and NF-kappaB activation
Rui et al., FASEB J 2005 (Inflammation) : NFkappaB and AP-1 differentially contribute to the induction of Mn-SOD and eNOS during the development of oxidant tolerance
Choi et al., J Biomed Sci 2005 : Chrysoeriol potently inhibits the induction of nitric oxide synthase by blocking AP-1 activation
Qian et al., Mol Cell Endocrinol 2007 : Transcriptional regulation of endothelial nitric oxide synthase expression in uterine artery endothelial cells by c-Jun/AP-1 ... We developed a c-Jun adenoviral expression system to overexpress c-Jun protein into UAEC to investigate the effects of c-Jun/AP-1 on NOS3 expression ... Lastly, the pharmacological AP-1 activator phorbol myristate acetate increased AP-1 binding, trans activated the wild-type but not the AP-1 mutant NOS3 promoter and dose-dependently stimulated UAEC NOS3 and c-Jun protein expression ... Hence, our data show that c-Jun/AP-1 regulates NOS3 transcription involving the proximal AP-1 site in the 5'-regulatory region of the sheep NOS3 gene
Hasselblatt et al., Proc Natl Acad Sci U S A 2007 (Drug-Induced Liver Injury...) : Hepatocyte survival in acute hepatitis is due to c-Jun/AP-1 dependent expression of inducible nitric oxide synthase
Kumar et al., Am J Physiol Lung Cell Mol Physiol 2008 : These data suggest a role of decreased AP-1 binding likely through c-Jun in the H ( 2 ) O ( 2 ) -mediated decrease in eNOS promoter activity
Polytarchou et al., Int J Cancer 2009 (Prostatic Neoplasms) : Inhibition of eNOS or the downstream effector soluble guanylate cyclase ( sGC ) completely suppressed HP-induced AP-1 activities that lead to PTN expression and cell migration
Passos et al., Am J Pathol 2009 (Inflammation) : MIP-1alpha ( -/- ) and CCR5 ( -/- ) mice displayed reduced astrocytosis and microgliosis in the hippocampus after Abeta ( 1-40 ) administration that was associated with decreased expression of cyclooxygenase-2 and inducible nitric oxide synthase , as well as reduced activation of nuclear factor-kappaB, activator protein-1 and cyclic AMP response element binding protein
Kwon et al., Endocrinology 1996 : Interleukin 1-induced Fos and Jun do not regulate inducible nitric oxide synthase in rat islets of Langerhans and RINm5F cells
Marks-Konczalik et al., J Biol Chem 1998 : Cytokine mediated transcriptional induction of the human inducible nitric oxide synthase gene requires both activator protein 1 and nuclear factor kappaB binding sites ... The involvement of AP-1 and NF-kappaB transcription factors in cytokine mediated induction of human inducible nitric oxide synthase ( hiNOS ) promoter activity was examined
Navarro-Antolín et al., Kidney Int Suppl 1998 : The potential participation of ROS and the transcription factor AP-1 in the regulation of eNOS gene expression is suggested