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CCL5 — JUN
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Tang et al., Arthritis Rheum 2010
(Osteoarthritis) :
CCL5 mediated
AP-1 luciferase activity and c-Jun binding to the AP-1 element were inhibited by Met-RANTES, rottlerin, and PP2
Li et al., J Clin Endocrinol Metab 2011
(Inflammation...) :
In IL-1ß- or TNF-a stimulated first trimester decidual cells, NF?B inhibitor suppressed production of all six chemokines ;
JUN NH2-terminal kinase inhibitor
inhibited secretion of CCL2, CCL4, and
CCL5 ; and MAPK kinase and p38 inhibitor decreased production of CXCL8