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DNASE1L3 — FOS
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Gresch et al., Neuroscience 2002
:
Pretreatment with MDL 100907 completely blocked
LSD induced
Fos-like immunoreactivity in medial prefrontal cortex and anterior cingulate cortex, but only partially blocked LSD induced Fos-like immunoreactivity in amygdala ... Double labeled immunohistochemistry revealed that
LSD did not
induce Fos-like immunoreactivity in cortical cells expressing 5-HT(2A) receptors, suggesting an indirect activation of cortical neurons
Reissig et al., Eur J Pharmacol 2008
:
d-LSD induced
c-Fos expression occurs in a population of oligodendrocytes in rat prefrontal cortex ... Although c-Fos positive cells were found in all cortical layers, they were most numerous in layers III, IV, and V.
d-LSD induced
c-Fos immunoreactivity was found in cells co-labeled with anti-neuron-specific enolase or anti-oligodendrocyte Oligo1 ... Astrocytes and microglia labeled with glial fibrillary acidic protein antibody and OX-42 antibody, respectively, did not display
LSD induced
c-Fos expression ... The present study demonstrates that
d-LSD induced expression of
c-Fos in the prefrontal cortex occurs in subpopulations of neurons and in oligodendrocytes, but not in pyramidal neurons, astrocytes, and microglia