Gene interactions and pathways from curated databases and text-mining

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DNASE1L3 — FOS

Text-mined interactions from Literome

Gresch et al., Neuroscience 2002 : Pretreatment with MDL 100907 completely blocked LSD induced Fos-like immunoreactivity in medial prefrontal cortex and anterior cingulate cortex, but only partially blocked LSD induced Fos-like immunoreactivity in amygdala ... Double labeled immunohistochemistry revealed that LSD did not induce Fos-like immunoreactivity in cortical cells expressing 5-HT(2A) receptors, suggesting an indirect activation of cortical neurons
Reissig et al., Eur J Pharmacol 2008 : d-LSD induced c-Fos expression occurs in a population of oligodendrocytes in rat prefrontal cortex ... Although c-Fos positive cells were found in all cortical layers, they were most numerous in layers III, IV, and V. d-LSD induced c-Fos immunoreactivity was found in cells co-labeled with anti-neuron-specific enolase or anti-oligodendrocyte Oligo1 ... Astrocytes and microglia labeled with glial fibrillary acidic protein antibody and OX-42 antibody, respectively, did not display LSD induced c-Fos expression ... The present study demonstrates that d-LSD induced expression of c-Fos in the prefrontal cortex occurs in subpopulations of neurons and in oligodendrocytes, but not in pyramidal neurons, astrocytes, and microglia