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ERBB2 — PIK3C2B

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: PIK3C2B → Complex of EGFR-ERBB2 (increases, EGFR/ERBB2 Activity, PIK3C2B Activity) Arcaro et al., Mol Cell Biol 2000*
  Evidence: Stimulation of quiescent cultures with EGF resulted in the rapid recruitment of both enzymes to a phosphotyrosine signaling complex that contained the EGF receptor and Erb-B2.
• WikiPathways Signaling Pathways in Glioblastoma: IGF1R/ERBB3/FGFR1/PDGFRA/PDGFRB/ERBB2/EGFR/FGFR2/MET → Complex of PIK3C2B-PIK3C2A-PIK3C2G (mim-stimulation)
  

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• MIPS CORUM EGFR-containing signaling complex: EGFR-containing signaling complex complex (EGFR-ERBB2-PIK3C2A-PIK3C2B) Arcaro et al., Mol Cell Biol 2000*
• IRef Corum Interaction: Complex of ERBB2-EGFR-PIK3C2B-PIK3C2A (association, coimmunoprecipitation) Arcaro et al., Mol Cell Biol 2000*
• IRef Hprd Interaction: PIK3C2B — ERBB2 (in vivo) Arcaro et al., Mol Cell Biol 2000*
• IRef Intact Interaction: ERBB2 — PIK3C2B (direct interaction, affinity chromatography technology) Arcaro et al., Mol Cell Biol 2000*
• IRef Intact Interaction: Complex of PIK3C2B-PIK3C2A-ERBB2 (association, anti bait coimmunoprecipitation) Arcaro et al., Mol Cell Biol 2000*