Megidish et al., J Biol Chem 2002
:
Furthermore, ectopic expression of PIAS1 induces p53 mediated expression of cyclin dependent kinase inhibitor p21 and G ( 1 ) arrest of the cell cycle in H1299 cells
Munarriz et al., Mol Cell Biol 2004
(Carcinoma, Small Cell...) :
PIAS-1 is expressed predominantly during S phase, and PIAS-1 overexpression reduces p73 mediated transcription of p21 , with a reduction of cells in G ( 1 ) and cell cycle reentry