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CDKN1A — HDAC11
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Xiao et al., J Cell Biochem 1999
:
Both Sp1 and Sp3 are responsible for
p21waf1 promoter activity
induced by
histone deacetylase inhibitor in NIH3T3 cells
Sowa et al., Cancer Res 1999
:
Sp3, but not Sp1, mediates the transcriptional
activation of the
p21/WAF1/Cip1 gene promoter by
histone deacetylase inhibitor
Xiao et al., J Biol Chem 2000
:
p300 collaborates with Sp1 and Sp3 in
p21 ( waf1/cip1 ) promoter activation
induced by
histone deacetylase inhibitor
Shin et al., Cancer Res 2000
(Stomach Neoplasms) :
The
p21 gene was
activated only by
histone deacetylase inhibitor
Claassen et al., Proc Natl Acad Sci U S A 2000
:
Repression of
p21 ( CIP1 ) transcription by c-Myc occurred at the promoter level in a region near the start site of transcriptional initiation and was
independent of
histone deacetylase activity
Huang et al., Oncogene 2000
(Breast Neoplasms) :
Activation of the
p21WAF1/CIP1 promoter independent of p53 by the
histone deacetylase inhibitor suberoylanilide hydroxamic acid ( SAHA ) through the Sp1 sites
Sowa et al., Biofactors 2000
(Colorectal Neoplasms...) :
As a model of this, we found that
histone deacetylase inhibitors such as butyrate or trichostatin A dramatically
stimulate the
p21/WAF1 gene promoter through the Spl sites, resulting in cell cycle arrest
Han et al., J Biol Chem 2001
:
Activation of
p21 ( WAF1/Cip1 ) transcription through Sp1 sites by
histone deacetylase inhibitor apicidin : involvement of protein kinase C
Burgess et al., Mol Pharmacol 2001
:
Up-regulation of
p21 ( WAF1/CIP1 ) by
histone deacetylase inhibitors reduces their cytotoxicity
Blagosklonny et al., Mol Cancer Ther 2002
:
By preventing deacetylation of histones,
histone deacetylase inhibitors ( HDIs ) transcriptionally
induce p21
Sowa et al., Nihon Eiseigaku Zasshi 2003
(Neoplasms) :
As a model of our hypothesis, we found that
histone deacetylase inhibitors such as butyrate and trichostatin A dramatically
stimulate the
p21/WAF1 gene promoter through the Sp1 sites, resulting in cell cycle arrest
Piekarz et al., Blood 2004
(Lymphoma, T-Cell) :
Treatment with depsipeptide, as well as other
histone deacetylase inhibitors,
caused induction of histone acetylation, induction of
p21 expression, and substantial apoptosis without significant cell cycle arrest