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BCL10 — IL7
Text-mined interactions from Literome
Sade et al., Eur J Immunol 2003
:
The protective effect was attenuated by pharmacological inhibitors of phosphatidylinositol-3 kinase (PI3K) with one exception : inhibition of PI3K did not abrogate
Bcl-x ( L ) expression in the
presence of
IL-7 ... Thus,
IL-7 regulates IAP-2 expression and inhibits dexamethasone induced apoptosis by activating Akt via PI3K dependent signaling, but
regulates Bcl-x ( L ) expression via a PI3K independent pathway in mature T cells
Banerjee et al., J Immunol 1998
(Cell Transformation, Viral) :
IL-7 also
delayed the decreases in the levels of c-Myc, Bcl-2, and
Bcl-xL that occur upon loss of v-Abl kinase activity
Soares et al., J Immunol 1998
:
IL-7 prevented the decrease in Bcl-2 and
Bcl-xL and induced cell cycling in up to 20 % of cord T cells after 8 days, resulting in a threefold increase in cord T cell numbers