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NGF — STAT3

Pathways - manually collected, often from reviews:

• NCI Pathway Database Neurotrophic factor-mediated Trk receptor signaling: STAT3 (STAT3) → NGF/NGFR-active (NTRK1/NGF/NTF3/NTRK3/BDNF/NTRK2/NTF4/NTRK2) (modification, collaborate)
  Ng et al., J Biol Chem 2006*
  Evidence: mutant phenotype, reporter gene, other species
• Reactome Reaction: NGF → STAT3 (reaction)

Text-mined interactions from Literome

Ng et al., J Biol Chem 2006 : Activation of TrkA by NGF triggered STAT3 phosphorylation at Ser-727, and enhanced the DNA binding and transcriptional activities of STAT3
Zhou et al., PloS one 2011 : Mitochondrial localized STAT3 is involved in NGF induced neurite outgrowth
Guo et al., Mol Cancer Ther 2013 (Neoplasm Invasiveness...) : NE-mediated activation of STAT3 was inhibited by blocking ß-adrenergic receptors ( AR ) and by blocking protein kinase A, but not through blocking a-AR. Blocking STAT3 could inhibit NE-induced NGF , MMP2, and MMP9 expression and attenuate the migratory, invasive ability and PNI of pancreatic cancer cells
Ihara et al., EMBO J 1997 : Dominant negative STAT3s mimicked NGF pretreatment, and NGF suppressed the IL-6 induced activation of STAT3, supporting the idea that STAT3 might regulate the differentiation of PC12 cells negatively ... These results suggest that neurite outgrowth of PC12 cells is regulated by the balance of MAP kinase and STAT3 signal transduction pathways, and that STAT3 activity can be regulated negatively by NGF