◀ Back to RHOA

CA2 — RHOA

Text-mined interactions from Literome

Nozu et al., Am J Physiol 1999 : Although an increase in RhoA did not require the presence of extracellular Ca2+ , the intracellular Ca2+ chelator 1, 2-bis ( 2-aminophenoxy ) ethane-N, N,N ', N'-tetraacetic acid-AM abolished the appearance of the RhoA band in response to CCK and carbachol
Rao et al., Am J Physiol Cell Physiol 2001 (Calcium Signaling) : These findings suggest that polyamine dependent cell migration is partially initiated by the formation of myosin II stress fibers as a result of Ca2+ activated RhoA activity
Sakurada et al., Circ Res 2003 : In this study, we demonstrate a novel Ca2+ dependent mechanism for activating RhoA in rabbit aortic VSM
Emmert et al., Am J Physiol Cell Physiol 2004 : In the presence or absence of Ca2+ , thrombin or lysophosphatidic acid (LPA) increased RhoA activity and Rhokinase activity, correlating with isometric tension development and myosin II regulatory light chain ( RLC ) phosphorylation
Yatani et al., Am J Physiol Heart Circ Physiol 2005 : In addition, expression of a dominant negative RhoA but not a dominant negative Rac-1 or Cdc42 also significantly decreased Ca2+ current density, which indicates that inhibition of Ca2+ channel activity by overexpression of Rho GDI-alpha is mediated by inhibition of RhoA
Stevenson et al., FEBS Lett 2004 : Uncoupling of GPCR and RhoA induced Ca2+-sensitization of chicken amnion smooth muscle lacking CPI-17
Singh et al., J Biol Chem 2007 : Depletion of extracellular Ca2+ also inhibited RhoA activation, indicating the requirement of Ca2+ entry in the response
Vandenbroucke et al., Ann N Y Acad Sci 2008 : Ca2+ activation of MLCK and RhoA disrupts junctions, whereas Rac1 and Cdc42 promote junctional assembly
Henstridge et al., FASEB J 2009 (Calcium Signaling) : The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA dependent Ca2+ signaling and NFAT activation
Arrigo et al., Conf Proc IEEE Eng Med Biol Soc 2008 : Ca2+ activation of MLCK and RhoA disrupts junctions, whereas Rac1 and Cdc42 promote junctional assembly
Huang et al., J Cell Sci 2011 : Slit-2 repels the migration of olfactory ensheathing cells by triggering Ca2+ dependent cofilin activation and RhoA inhibition
Jiang et al., Experimental biology and medicine (Maywood, N.J.) 2011 : Over expressing transient receptor potential cation channel 6 in podocytes induces cytoskeleton rearrangement through increases of intracellular Ca2+ and RhoA activation
Fernández-Tenorio et al., Eur J Pharmacol 2012 (Calcium Signaling) : Tonic arterial contraction mediated by L-type Ca2+ channels requires sustained Ca2+ influx, G protein associated Ca2+ release, and RhoA/ROCK activation