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NUP43 — SRC
Text-mined interactions from Literome
Xie et al., Eur J Biochem 2002
:
The signaling pathways that are rapidly elicited by the interaction of ouabain with Na ( + ) /K ( + ) -ATPase, and are independent of changes in intracellular Na ( + ) and K ( + ) concentrations, include activation of Src kinase, transactivation of the epidermal growth factor receptor by
Src ,
activation of Ras and
p42/44 mitogen activated protein kinases, and increased generation of reactive oxygen species by mitochondria
Wang et al., J Cell Physiol 2011
:
Engagement of G ( i/o ) -- and G ( q ) -coupled ET ( B ) receptors by ET-1 led to activation of
c-Src dependent phosphoinositide 3-kinase (PI3K)/Akt and
p42/p44 mitogen activated protein kinase ( MAPK ) and then activated transcription factor nuclear factor-?B ( NF-?B )
Oldham et al., Oncogene 1998
(Cell Transformation, Neoplastic) :
Second, whereas both
Src and Ras
caused upregulation of the
p42 and p44 mitogen activated protein kinases ( MAPKs ), only Ras transformation was blocked by the inhibition of MAPK activation by treatment with the PD 98059 MEK inhibitor