Gene interactions and pathways from curated databases and text-mining

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LTBR — NFKB1

Text-mined interactions from Literome

Matsushima et al., J Exp Med 2001 : Essential role of nuclear factor (NF)-kappaB inducing kinase and inhibitor of kappaB (IkappaB) kinase alpha in NF-kappaB activation through lymphotoxin beta receptor , but not through tumor necrosis factor receptor I
Yin et al., Science 2001 : Defective lymphotoxin-beta receptor induced NF-kappaB transcriptional activity in NIK-deficient mice
Luftig et al., J Biol Chem 2001 : Effects of the NIK aly mutation on NF-kappaB activation by the Epstein-Barr virus latent infection membrane protein, lymphotoxin beta receptor , and CD40
Smith et al., J Immunol 2001 (Arthritis, Rheumatoid) : NF-kappaB inducing kinase is dispensable for activation of NF-kappaB in inflammatory settings but essential for lymphotoxin beta receptor activation of NF-kappaB in primary human fibroblasts
Saitoh et al., FEBS Lett 2002 : Lymphotoxin-beta receptor mediates NEMO independent NF-kappaB activation
Müller et al., J Biol Chem 2003 : Lymphotoxin beta receptor induces sequential activation of distinct NF-kappa B factors via separate signaling pathways ... Lymphotoxin beta receptor (LTbetaR) induced activation of NF-kappaB in mouse embryo fibroblasts was mediated by the classical pathway and by an alternative or second pathway
Chen et al., Oncogene 2003 : Gene knockout study, however, suggests that NIK is dispensable for TNF-R1- but required for lymphotoxin-beta receptor induced NF-kappaB activation
Qin et al., J Immunol 2007 : Two-week-old TRAF6-deficient mice showed severe defects in B cell follicle and marginal zone formation, similar to mutant mice defective in lymphotoxin (Lt) beta receptor ( LtbetaR ) signal induction of nonclassical NF-kappaB activation
Bista et al., J Biol Chem 2010 : TRAF3 controls activation of the canonical and alternative NFkappaB by the lymphotoxin beta receptor ... Analysis of NFkappaB signaling in cell lines with functionally intact NFkappaB pathway but lacking LTBR mediated induction of NFkappaB target genes revealed an inverse association of cellular TRAF3 levels with LTBR-specific defect in canonical NFkappaB activation