Gene interactions and pathways from curated databases and text-mining

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IL15 — JAK3

Text-mined interactions from Literome

To et al., Br J Cancer 2004 (Cell Transformation, Neoplastic...) : The interleukin mediated Janus kinase ( JAK ) /STAT pathway plays a crucial role in carcinogenesis
Walker et al., Arch Virol Suppl 2005 (Ehrlichiosis) : Ehrlichiae attach to L-selectin and E-selectin, inhibit phagolysosomal fusion, apoptosis, and JAK/STAT activation, and downregulate IL-12, IL-15 , IL-18, TLR2 and 3, and CD14
Waldmann et al., Int Rev Immunol 1998 : In mast cells, IL-15 signaling involves JAK-2 and STAT-5 activation rather than the JAK-1 and JAK-3 as well as the STAT-3 and STAT-5 used by both IL-2 and IL-15 in activated T cells