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DES — IGF1
Text-mined interactions from Literome
Turner et al., Endocrinology 1992
:
Uterus and liver served as positive and negative control tissues, respectively, for the
effects of
DES on
IGF-I mRNA levels in OVX rats ; mRNA levels were increased in uterus and decreased in liver after hormone treatment
Czifra et al., Cell Signal 2006
:
In human muscle,
IGF-I stimulated proliferation and fusion of the cells and the expression of the differentiation marker
desmin
Tomas et al., Biochem J 1991
(Diabetes Mellitus, Experimental...) :
Des ( 1-3 )
IGF-I induced binding proteins, but had only a slight effect on measured IGF-I concentrations
Politis et al., Endocrine 1995
:
Not unexpectedly, insulin-like growth factor
(IGF)-I ,
Des ( 1-3 ) IGF-I and IGF-II
increased mammary epithelial u-PA activity on a per cell basis and u-PA mRNA levels, thus, mimicking the effect of insulin
Tomas et al., Diabetes 1996
(Body Weight...) :
Des ( 1-3 )
IGF-I increased liver glycogen additively with insulin but reduced glucosuria only when given with 5.6 nmol insulin per day, indicating the possibility of a facilitatory effect, perhaps via increased insulin sensitivity