Amrani et al., Mol Pharmacol 2000
:
These data suggest that TNFR1 , through a TNF receptor associated factor 2-NF-kappaB signaling pathway, mediates TNFalpha induced expression of ICAM-1 on ASM cells by involving a thapsigargin-sensitive signaling pathway
Cook et al., Invest Ophthalmol Vis Sci 2008
:
Upregulation of TNFR1 expression by priming with TAPI-2 and IFNgamma resulted in enhanced ICAM-1 expression in response to TNFalpha stimulation ( significant change in the slope of the dose-response curve )