Gene interactions and pathways from curated databases and text-mining

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ICAM1 — NOS1

Text-mined interactions from Literome

Guan et al., Chin Med J (Engl) 2003 (Arteriosclerosis) : The ox-LDL can significantly increase the expression of ICAM-1 and inhibit the expression of NO and NOS in a dose dependent manner
Dal Secco et al., Nitric Oxide 2006 : Moreover, genetic ( iNOS-/- mice ) or pharmacological inhibition of NOS or of sGC enhanced LPS induced ICAM-1 expression on mesenteric microcirculation vessels of WT mice
Heo et al., Immunol Lett 2008 (Inflammation) : Moreover, NOS inhibitor ( L-NAME ) and anti-TLR 4mAb reduced the LPS induced NO, IL-8 and VEGF production and ICAM-1 expression
Martinelli et al., Mol Biol Cell 2009 : ICAM-1 mediated endothelial nitric oxide synthase activation via calcium and AMP activated protein kinase is required for transendothelial lymphocyte migration
Ning et al., PloS one 2013 (Inflammation...) : In addition, NaHS treatment prevented the increase of nitric oxide, Intercellular Adhesion Molecule 1 ( ICAM-1 ) and interleukin (IL)-6 production and inducible nitric oxide synthase activation induced by TNF-a
Fukuzawa et al., Immunol Lett 1997 : Nicotinamide, a pellagra-preventive factor, has multiple functions such as inhibition of poly-ADP-ribose synthetase, inhibition of inducible nitric oxide synthase , free radical scavenging and suppression of major histocompatibility complex class II expression and ICAM-1 expression on endothelial cells