Gene interactions and pathways from curated databases and text-mining

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EGFR — VCAM1

Text-mined interactions from Literome

Baker et al., Mol Immunol 2008 : These results suggest that P2Y2R activation in salivary gland cells increases the EGFR dependent expression of VCAM-1 and the binding of lymphocytes, a pathway relevant to inflammation associated with SS
Lin et al., Toxicol Appl Pharmacol 2008 : LPS stimulated Src, PYK2, EGFR, and Akt phosphorylation and VCAM-1 expression were attenuated by the inhibitors of Src ( PP1 ), EGFR ( AG1478 ), PI3-K ( LY294002 and wortmannin ), and Akt ( SH-5 ), respectively, or transfection with siRNAs of Src or Akt and shRNA of p110