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EGFR — FPR1
Text-mined interactions from Literome
Huang et al., Cancer Res 2007
(Brain Neoplasms...) :
The transactivation of EGFR contributes to the biological function of FPR in glioblastoma cells because inhibition of
EGFR phosphorylation significantly
reduced FPR agonist induced tumor cell chemotaxis and proliferation
El Zein et al., Cell Signal 2010
:
Tyrphostin AG1478, the EGFR inhibitor, inhibits fMLP and NGF associated ROS production, fMLP associated CD11b upregulation and NGF induced TrkA phosphorylation ; K252a, the NGF receptor inhibitor, inhibits fMLP or EGF associated ROS production, CD11b expression and EGF induced EGFR phosphorylation ; cyclosporine H, the
FPR inhibitor inhibits EGF or NGF associated ROS production, EGF associated CD11b upregulation and
prevents EGFR and TrkA phosphorylation by their respective ligand EGF and NGF