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EGF — TH

Text-mined interactions from Literome

Futamura et al., Mol Psychiatry 2003 : EGF-treatment induced transient impairment in tyrosine hydroxylase expression
Halegoua et al., Cell 1980 (Pheochromocytoma) : EGF but not insulin enhances the phosphorylation of tyrosine hydroxylase
Anastasiadis et al., Brain Res 1996 : Regulation of tyrosine hydroxylase and tetrahydrobiopterin biosynthetic enzymes in PC12 cells by NGF, EGF and IFN-gamma ... Rp-cAMP, an inhibitor of cAMP mediated responses, blocked the induction of tyrosine hydroxylase by NGF or EGF ; inhibition of protein kinase C partially blocked the EGF effect, but not the NGF effect, NGF also induced GTP cyclohydrolase in a cAMP dependent manner, while the EGF effect was not blocked by Rp-cAMP or protein kinase C inhibitors ... Our results suggest that both tyrosine hydroxylase and GTP cyclohydrolase are induced in a coordinate and transcription dependent manner by NGF and EGF , while conditions exist where the induction of tyrosine hydroxylase and GTP cyclohydrolase is not coordinately regulated