Gene interactions and pathways from curated databases and text-mining

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CCR7 — TGFB1

Text-mined interactions from Literome

Ogata et al., Blood 1999 : We observed here that TGF-beta1 not only inhibited the expression of CCR7 in DCs and DC precursors derived from HPCs, but also inhibited the migration of these cells in response to SLC
Ahmadzadeh et al., J Immunol 2005 (Melanoma) : Moreover, TGF-beta1 induced a modest expression of CCR7 on Ag-activated memory CD8 T cells
Ju et al., Eur J Immunol 2007 : TGF-beta1 also induced expression of the chemokine receptor CCR7 and enhanced DC migration towards CCR7 ligand ELC
Zhang et al., Blood 1999 : In the absence of TNFalpha, TGF-beta1 markedly suppressed the expression of CIITA and CCR7 mRNAs in GM-CSF + SCF stimulated Lin-c-kit+ HPCs at either day 6 or day 12 and induced the differentiation solely into monocytes/macrophages as evident in morphology, active phagocytic, and endocytic activities