Gene interactions and pathways from curated databases and text-mining

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AVP — TRH

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Ciosek et al., J Physiol Pharmacol 2002 (Dehydration) : Under conditions of equilibrated water metabolism TRH diminished significantly the hypothalamic and neurohypophysial AVP and OT content but was without the effect on plasma oxytocin level ; however, TRH in a dose of 100 ng/100 g b.w. raised plasma AVP level
Ciosek et al., Postepy Hig Med Dosw 2007 (Dehydration...) : The results showed that : TRH acts as a stimulator of oxytocin release into the blood by equilibrated water-electrolyte metabolism, TRH acts in the central nervous system as an inhibitory neuromodulator of vasopressin and oxytocin release from the hypothalamo-neurohypophysial system under in vitro conditions, by osmotic stimulation, as well as in females during lactation, TRH inhibits AVP release in acute bleeding provoked hypovolemia and alters the circadian rhythm of vasopressin and oxytocin release
Husain Jawadi et al., Horm Res 1984 (Hypothyroidism) : Effect of TRH on plasma arginine vasopressin
Sowers et al., Horm Res 1976 (Hypothyroidism) : Effect of TRH on serum arginine vasopressin in euthyroid and hypothyroid subjects ... To test the effect of thyrotropin releasing hormone (TRH) on serum arginine vasopressin (AVP) in euthyroid and hypothyroid individuals, 500 mug of TRH was administered to four euthyroid subjects and three patients with primary hypothyroidism