◀ Back to ANXA6

ANXA6 — TLR3

Text-mined interactions from Literome

Lehner et al., Immunol Lett 2005 : However, IL-12p70 production in response to Toll-like receptor ( TLR ) stimulating agents plus IFN-gamma was consistently lower in AIMV medium although also under serumfree culture conditions, nanogram quantities of IL-12 were produced
Agrawal et al., J Immunol 2006 (Encephalomyelitis, Autoimmune, Experimental...) : Consistent with this observation, dendritic cells from ERK1 ( -/- ) mice show enhanced IL-12p70 and reduced IL-10 secretion in response to TLR stimulation
Bekeredjian-Ding et al., J Immunol 2006 : T cell independent, TLR induced IL-12p70 production in primary human monocytes
Taneichi et al., Clin Immunol 2008 (Agammaglobulinemia...) : Stimulation with TLR2, TLR4 and TLR7/8 ligands, as well as TLR3 ligand, resulted in significantly lower production of TNF-alpha, but neither IL-6 nor IL-12p70 , by DCs from XLA patients in comparison to normal controls
Kollmann et al., J Immunol 2009 : In response to most TLR ligands, neonatal innate immune cells, including monocytes and conventional and plasmacytoid dendritic cells produced less IL-12p70 and IFN-alpha ( and consequently induced less IFN-gamma ), moderately less TNF-alpha, but as much or even more IL-1beta, IL-6, IL-23, and IL-10 than adult cells
Belderbos et al., Pediatr Allergy Immunol 2012 (Hypersensitivity) : Of innate immune variables, TLR3 mediated IL-12p70 production was highly associated with environmental exposures ( pets, breastfeeding and mode of delivery ), whereas TLR9 mediated cytokine responses were not associated with any environmental factor
Liu et al., Eur J Immunol 2012 : This indicates that IFN-a increased the sensitivity of monocytes to IL-10, and as a result, TLR induced IL-12p70 by IFN pretreated cells was suppressed ... In summary, we demonstrate that one of the consequences of priming human APCs with IFN is to promote the cells ' sensitivity to IL-10, which leads to the inhibition of TLR induced IL-12p70 production
Compté et al., PloS one 2013 : The aim of our study was to define the relative contribution of age and clinical status on TLR induced interleukin (IL)-12p70 and IL-23 production as these cytokines play an important role in the protection against intracellular and extracellular pathogens, respectively