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ANGPT2 — CYP11B2

Text-mined interactions from Literome

Li et al., Toxicol Appl Pharmacol 2004 : Despite the fact that PCB126 acted in synergy with both potassium and angiotensin II (Ang II) in activation of aldosterone synthesis, PCB126 only modestly increased CYP11B2 mRNA expression in the presence of Ang II contrary to the synergistic transcriptional induction elicited by PCB126 and potassium
Romero et al., Endocrinology 2006 (Calcium Signaling) : RGS2 overexpression specifically decreases aldosterone secretion through a decrease in Ang II-mediated aldosterone synthase induced expression
Rajamohan et al., Antioxid Redox Signal 2012 : These Ang II-evoked effects were either abolished or attenuated by pretreatment of cells with either Ang II type I receptor ( AT(1)R ) antagonist, or antioxidants or Nox inhibitor or siRNA silencing of Nox1, 2 and 4, or inhibitors of phospholipase C and protein kinase C. Exogenous H ( 2 ) O ( 2 ) mimicked the facilitatory effects of Ang II on CYP11B2 activity, mRNA, and protein expression, and these changes were significantly reduced by PEG-catalase
Briones et al., Hypertension 2012 (Diabetes Complications...) : In 3T3-L1 adipocytes, Ang II stimulation increased aldosterone secretion and CYP11B2 expression