Gene interactions and pathways from curated databases and text-mining

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LRP1 — RAC1

Text-mined interactions from Literome

Ma et al., J Cell Biol 2002 : Neutralizing the activity of LRP-1 with receptor associated protein (RAP) increased Rac1 activation and cell migration in MEFs and L929 cells ... Thus, LRP-1 regulates two signaling proteins in the same cell ( Rac1 and ERK ), both of which may impact on cell migration
Mantuano et al., J Biol Chem 2010 : Known LRP1 ligands, including matrix metalloprotease-9, tissue-type plasminogen activator, and alpha(2)-macroglobulin activated Rac1 in LRP1 expressing Schwann cells