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LRP1 — RAC1
Text-mined interactions from Literome
Ma et al., J Cell Biol 2002
:
Neutralizing the activity of
LRP-1 with receptor associated protein (RAP)
increased Rac1 activation and cell migration in MEFs and L929 cells ... Thus,
LRP-1 regulates two signaling proteins in the same cell (
Rac1 and ERK ), both of which may impact on cell migration
Mantuano et al., J Biol Chem 2010
:
Known
LRP1 ligands, including matrix metalloprotease-9, tissue-type plasminogen activator, and alpha(2)-macroglobulin
activated Rac1 in LRP1 expressing Schwann cells