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CXCL10 — PTGS2
Text-mined interactions from Literome
Kanda et al., J Invest Dermatol 2002
(Carcinoma, Squamous Cell...) :
We examined the in vitro
effects of
cyclooxygenase-2 inhibitor NS398 on
IP-10 production in human epidermoid carcinoma A431
Põld et al., Cancer Res 2004
(Carcinoma, Non-Small-Cell Lung...) :
Cyclooxygenase-2 dependent expression of angiogenic
CXC chemokines ENA-78/CXC Ligand (CXCL) 5 and interleukin-8/CXCL8 in human non-small cell lung cancer ... To elucidate the
role of
COX-2 in the in vitro and in vivo expression of two known NSCLC angiogenic peptides,
CXC ligand ( CXCL ) 8 and CXCL5, we studied two COX-2 gene modified NSCLC cell lines, A549 and H157 ...
COX-2 overexpression
enhanced the in vitro expression of both
CXCL8 and CXCL5
Laine et al., Biochem Biophys Res Commun 2007
:
Palmitic acid ( PA ), the predominant saturated FFA released from adipose tissue, but not unsaturated FFA,
induced an approximately 6-fold ( p < 0.05 ) increase in
IP-10 gene expression ( and 2- to 4-fold increases in IL-8, MCP-1,
COX-2 , and MIG )
Brant et al., Toxicological sciences : an official journal of the Society of Toxicology 2009
:
Consistent with our previous findings that Ni and MALP-2 stimulates the induction of CXCL8 via a COX-2 mediated pathway,
CXCL1 , CXCL5, and VEGF release were also
regulated by
COX-2