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IGF1 — PSMG1
Text-mined interactions from Literome
Jamen et al., J Neurochem 2002
(MAP Kinase Signaling System) :
In cerebellar granule cells,
IGF-1 and brain derived neurotrophic factor (BDNF) also
stimulated the activity of the
PAC1 promoter ... In cerebellar granule cells,
IGF-1 and brain derived neurotrophic factor (BDNF) also
stimulated the activity of the
PAC1 promoter ... NGF and
IGF-1 increased endogenous
PAC1 mRNA levels, and the NGF induced up-regulation is the result of an increase in transcription from PAC1 promoter instead of an increase in mRNA stability
Delcourt et al., EMBO J 2007
:
PAC1R transactivation was responsible for a large fraction of the IGF-1 associated phosphoproteome and
played a critical role in the antiapoptotic activity of
IGF-1