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IL10 — NFKBIA

Text-mined interactions from Literome

Alpert et al., J Biol Chem 1999 : In addition, sorbitol and H ( 2 ) O ( 2 ) blocked TNF induced but not interleukin-1 induced IkappaBalpha phosphorylation, whereas arsenite inhibited IkappaBalpha phosphorylation induced by TNF and interleukin-1
Molina-Holgado et al., J Neurochem 2002 (Cardiovirus Infections) : IL-4 and IL-10 caused an accumulation of IkappaBalpha in TMEV infected astrocytes without affecting IkappaBbeta levels ... Indeed, IL-4 or IL-10 up-regulated IkappaBalpha mRNA levels after TMEV infection
Mazighi et al., Am J Physiol Heart Circ Physiol 2004 (Hyperplasia...) : In LPS stimulated rat SMCs, 1 ng/ml recombinant murine IL-10 ( mIL-10 ) reduced I-kappaBalpha and I-kappaBbeta degradation, NF-kappaB activation, as well as the expression of the NF-kappaB dependent gene IL-6 by 32 %, 31 %, 75 %, and 19 %, respectively ( P < 0.05 for all )
Soloff et al., Mol Hum Reprod 2004 : We were unable to detect any significant differences between primary and immortalized cells in signal pathways such as epidermal growth factor stimulated epidermal growth factor receptor phosphorylation, insulin stimulated Akt phosphorylation, oxytocin and lysophosphatidic acid stimulated extracellular signal regulated kinase 1 and 2 phosphorylation, myosin light chain phosphorylation, and interleukin-1 induction of IkappaBalpha degradation
Gómez-Quiroz et al., Liver Int 2005 (Carcinoma, Hepatocellular...) : Moreover, IL-10 did not induce the degradation of I kappa B-alpha in cellular extract from rat primary cultured cells
Newton et al., J Pharmacol Exp Ther 2007 (Pulmonary Disease, Chronic Obstructive) : In A549 cells, interleukin (IL)-1beta and tumor necrosis factor (TNF) alpha increased phosphorylation of IkappaBalpha , and this was followed by loss of IkappaBalpha, induction of NF-kappaB DNA binding, and the induction of NF-kappaB dependent transcription
Sarkar et al., Mol Cell Biol 2011 : RNA binding protein AUF1 regulates lipopolysaccharide induced IL10 expression by activating IkappaB kinase complex in monocytes
Lentsch et al., J Clin Invest 1997 : Northern blot analysis of lung mRNA showed that, in the presence of IgG immune complexes, IL-10 and IL-13 augmented I kappa B alpha mRNA expression
Shames et al., Shock 1998 (Endotoxemia) : We hypothesized that IL-10 prevents human monocyte NF-kappaB activation and resultant TNF-alpha production by stabilization of IkappaB-alpha ... The purpose of this study was to determine the effect of IL-10 on lipopolysaccharide (LPS) induced human monocyte TNF-alpha production, NF-kappaB activation, and IkappaB-alpha degradation ... IL-10 appears to prevent activation of NF-kappaB by preserving IkappaB-alpha protein levels, leading to a reduction in TNF-alpha release