Gene interactions and pathways from curated databases and text-mining

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C1ORF228 — IL10

Text-mined interactions from Literome

Zhou et al., Mol Cell Biol 2004 : Interleukin-10 inhibits interleukin-12 p40 gene transcription by targeting a late event in the activation pathway
Olleros et al., Immunology 2007 (Granuloma...) : Interleukin-12p40 overexpression promotes interleukin-12p70 and interleukin-23 formation but does not affect bacille Calmette-Guérin and Mycobacterium tuberculosis clearance
Chung et al., J Infect Dis 2013 (Leprosy, Lepromatous...) : Galectin-3 enhanced monocyte interleukin 10 production to a TLR2/1 ligand, whereas interleukin 12p40 secretion was unaffected
Scharton-Kersten et al., J Exp Med 1997 (Acute Disease...) : Interferon consensus sequence binding protein-deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 induction