◀ Back to HNRNPF
HNRNPF — PPARG
Text-mined interactions from Literome
Hammad et al., Am J Pathol 2004
(Asthma...) :
In the present report, we investigated the possibility that, by targeting
DCs ,
PPAR-gamma activation may be
involved in the regulation of the pulmonary immune response to allergens
Appel et al., Blood 2005
:
Activation of
PPAR-gamma resulted in a reduced stimulation of
DCs via the TLR ligands 2, 3, 4, and 7, characterized by down-regulation of costimulatory and adhesion molecules and reduced secretion of cytokines and chemokines involved in T-lymphocyte activation and recruitment
Szatmari et al., Blood 2007
:
Our data show that
PPARgamma acts as a mostly positive transcriptional regulator in human developing
DCs , acting primarily through controlling genes involved in lipid metabolism and via this, indirectly modifying the immune phenotype