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FOS — STAR
Text-mined interactions from Literome
Manna et al., Mol Endocrinol 2004
:
The integrity of the sequence-specific AP-1 element in StAR gene transcription was assessed using the AP-1 family members, Fos ( c-Fos, Fra-1, Fra-2, and Fos B ) and Jun ( c-Jun, Jun B, and Jun D ), which demonstrated the
involvement of
Fos and Jun in
StAR gene transcription to varying degrees
Rincon Garriz et al., Endocrinology 2009
:
Overexpression of a dominant negative form of
c-Fos with adenoviral vectors
inhibited StAR mRNA and
StAR protein expression as well as aldosterone biosynthesis in response to AngII
Manna et al., Endocrinology 2011
:
Further studies pointed out that the regulatory events effected by PKD are associated with cAMP response element binding protein ( CREB ) and
c-Jun/c-Fos mediated transcription of the
StAR gene