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EGF — RPS6KA1

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: RPS6KA1 → EGF (increases) Olsen et al., Cell 2006*
  Evidence: We have detected 6,600 phosphorylation sites on 2,244 proteins and have determined their temporal dynamics after stimulating HeLa cells with epidermal growth factor (EGF) and recorded them in the Phosida database

Text-mined interactions from Literome

Richards et al., Mol Cell Biol 2001 : Here we show that prior to nuclear translocation, epidermal growth factor stimulated RSK1 transiently associates with the plasma membrane
Shah et al., J Steroid Biochem Mol Biol 2006 : Whereas, selective inhibition of EGF-R kinase with AG1478 caused complete inhibition of EGF induced ERK/RSK-1/CREB activation , it caused only partial reduction ( 30-40 % ) of such ET-1 induced responses ... Activation of ERK/RSK-1/CREB by both ET-1 and EGF was abolished by inhibition of Src, indicating its central role in ET-1 signaling in BAG cells
Gao et al., J Biol Chem 2009 : Similarly, in intact cells, cAMP mediated phosphorylation of Bcl-xL/Bcl-2 associated death promoter on Ser-115, the PKA site, was reduced when RSK1 was activated by epidermal growth factor , and this effect was blocked by peptide E, but not by peptide A