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AKT2 — CNR2
Text-mined interactions from Literome
Viscomi et al., J Neurosci 2009
:
Analysis of CB2R triggered signal transduction demonstrated that in axotomized neurons,
CB2R regulated
Akt and JNK phosphorylation through a PI3K dependent pathway, whereas other major signaling routes that are dependent on CB2R, such as ERK1/2 and p38, were not involved
Catani et al., Cell Mol Life Sci 2010
:
Instead, AEA binding to type-1
cannabinoid receptor activates
Akt , which regulates, through phosphorylation of Bad, the interactions among different Bcl-2 family members
Merighi et al., Br J Pharmacol 2012
(Inflammation) :
We examined the
effects of µ-opioid and
CB(2) receptor stimulation on phosphorylation of MAPKs and
Akt and on IL-1ß, TNF-a, IL-6 and NO production in primary mouse microglial cells