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CDKN1A — TGFB3
Text-mined interactions from Literome
Hu et al., J Biol Chem 1999
:
The MEK pathway is required for
stimulation of
p21 ( WAF1/CIP1 ) by
transforming growth factor-beta
Pardali et al., J Biol Chem 2000
:
Role of Smad proteins and transcription factor Sp1 in
p21 ( Waf1/Cip1 )
regulation by
transforming growth factor-beta
Lunz et al., Am J Pathol 2001
(Chronic Disease) :
In vitro, nuclear
p21 ( WAF1/Cip1 ) expression is increased in large and multinucleated BECs, and is
induced by
transforming growth factor ( TGF ) -beta
Sasaki et al., J Biol Chem 2001
:
We found that Hgs associated physically with
transforming growth factor-beta activated kinase 1 ( TAK1 ) and
p21 activated kinase 1 (Pak1) , which mediate the activation of c-Jun N-terminal kinase and serum response factor, respectively, leading to transactivation via the serum-response element and cyclic AMP-response element
Ijichi et al., Oncogene 2004
(Pancreatic Neoplasms) :
Smad4 independent
regulation of
p21/WAF1 by
transforming growth factor-beta
Brizzi et al., FASEB J 2004
(Albuminuria...) :
We found that, unlike high glucose ( HG ) and Amadori adducts, advanced glycation end products (AGE) and
transforming growth factor-beta ( TGF-beta )
induced p21waf expression and accumulation of MC in G0/G1
Kokkinakis et al., Mol Cancer Ther 2005
(Adenocarcinoma...) :
Inhibition of cell cycle progression correlates with loss of hyperphosphorylated Rb and up-regulation of
p21 via p53 and/or
transforming growth factor-beta ( TGF-beta )
activation depending on p53 status
Adesina et al., Hum Pathol 2007
(Hepatoblastoma...) :
FOXG1 has been implicated in the repression of
transforming growth factor beta induced expression of
p21cip1 and cytostasis
Hasegawa et al., Cancer Sci 2007
(Biliary Tract Neoplasms) :
Restoration of RUNX3 enhances
transforming growth factor-beta dependent
p21 expression in a biliary tract cancer cell line
Siegenthaler et al., Dev Biol 2008
:
Most of these sites do not express Foxg1, a transcription factor that inhibits
transforming growth factor ( TGF ) beta dependent upregulation of
p21
Nakamura et al., In Vitro Cell Dev Biol Anim 2010
:
By quantitative reverse transcription-polymerase chain reaction assay, we found that the
TGF-beta3 resulted in an increased level of expression of p15Ink4b and
p21Cip1 , suggesting that the TGF-beta3 inhibited the taste epithelial cell proliferation through inhibiting G1cyclin-Cdk complexes
Datto et al., Mol Cell Biol 1997
:
The viral oncoprotein E1A blocks
transforming growth factor beta mediated induction of
p21/WAF1/Cip1 and p15/INK4B
Grau et al., Cancer Res 1997
(Adenocarcinoma...) :
Induction of
p21waf1 expression and growth inhibition by
transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells