Gene interactions and pathways from curated databases and text-mining

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CDKN1A — TGFB3

Text-mined interactions from Literome

Hu et al., J Biol Chem 1999 : The MEK pathway is required for stimulation of p21 ( WAF1/CIP1 ) by transforming growth factor-beta
Pardali et al., J Biol Chem 2000 : Role of Smad proteins and transcription factor Sp1 in p21 ( Waf1/Cip1 ) regulation by transforming growth factor-beta
Lunz et al., Am J Pathol 2001 (Chronic Disease) : In vitro, nuclear p21 ( WAF1/Cip1 ) expression is increased in large and multinucleated BECs, and is induced by transforming growth factor ( TGF ) -beta
Sasaki et al., J Biol Chem 2001 : We found that Hgs associated physically with transforming growth factor-beta activated kinase 1 ( TAK1 ) and p21 activated kinase 1 (Pak1) , which mediate the activation of c-Jun N-terminal kinase and serum response factor, respectively, leading to transactivation via the serum-response element and cyclic AMP-response element
Ijichi et al., Oncogene 2004 (Pancreatic Neoplasms) : Smad4 independent regulation of p21/WAF1 by transforming growth factor-beta
Brizzi et al., FASEB J 2004 (Albuminuria...) : We found that, unlike high glucose ( HG ) and Amadori adducts, advanced glycation end products (AGE) and transforming growth factor-beta ( TGF-beta ) induced p21waf expression and accumulation of MC in G0/G1
Kokkinakis et al., Mol Cancer Ther 2005 (Adenocarcinoma...) : Inhibition of cell cycle progression correlates with loss of hyperphosphorylated Rb and up-regulation of p21 via p53 and/or transforming growth factor-beta ( TGF-beta ) activation depending on p53 status
Adesina et al., Hum Pathol 2007 (Hepatoblastoma...) : FOXG1 has been implicated in the repression of transforming growth factor beta induced expression of p21cip1 and cytostasis
Hasegawa et al., Cancer Sci 2007 (Biliary Tract Neoplasms) : Restoration of RUNX3 enhances transforming growth factor-beta dependent p21 expression in a biliary tract cancer cell line
Siegenthaler et al., Dev Biol 2008 : Most of these sites do not express Foxg1, a transcription factor that inhibits transforming growth factor ( TGF ) beta dependent upregulation of p21
Nakamura et al., In Vitro Cell Dev Biol Anim 2010 : By quantitative reverse transcription-polymerase chain reaction assay, we found that the TGF-beta3 resulted in an increased level of expression of p15Ink4b and p21Cip1 , suggesting that the TGF-beta3 inhibited the taste epithelial cell proliferation through inhibiting G1cyclin-Cdk complexes
Datto et al., Mol Cell Biol 1997 : The viral oncoprotein E1A blocks transforming growth factor beta mediated induction of p21/WAF1/Cip1 and p15/INK4B
Grau et al., Cancer Res 1997 (Adenocarcinoma...) : Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells