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CDKN1A — KLF6

Text-mined interactions from Literome

Zhang et al., J Biol Chem 2000 : The gut enriched Kruppel-like factor ( Kruppel-like factor 4 ) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter
Wu et al., Oncogene 2004 : In addition, KLF2 upregulates p21WAF1/CIP1 expression
Pan et al., Zhonghua Gan Zang Bing Za Zhi 2006 (Carcinoma, Hepatocellular...) : Unlike the wild-type KLF6, cancer derived KLF6 mutants neither suppressed growth nor induced p21WAF1 following transfection into culture cells
Narla et al., Oncogene 2007 (Carcinoma, Hepatocellular...) : To address this issue, we have generated two genetic mouse models to define the in vivo role of KLF6 in regulating cell proliferation and p21 expression
Teixeira et al., Int J Cancer 2007 (Carcinoma, Squamous Cell...) : We also tested the effect of KLF6 inhibition in HNSCC cell lines on proliferation and p21 expression
Calderon et al., J Biol Chem 2012 : We propose a novel model of LCoR function in which promoter bound KLF6 inhibits transcription of the CDKN1A gene and other genes as well by tethering a transcriptional corepressor complex containing LCoR, with specific contributions by CtBP1 and HDACs
Song et al., Biochem Biophys Res Commun 2012 (Papilloma) : Furthermore, KLF10 dose-dependently activated p21 ( WAF1/CIP1 ) transcription, which was independent of p53 and Sp1 binding sites in p21 ( WAF1/CIP1 ) promoter