Niimi et al., J Cell Biol 2007
:
Both transcriptional induction of the Notch ligand Jagged1 by TGF-beta and endogenous levels of the Notch effector CSL contribute to p21 induction and epithelial cytostasis
Ban et al., Cancer Res 2008
(Sarcoma, Ewing) :
Conversely, forced expression of JAG1 , activated NOTCH3, or HEY1 induced p53 and p21 ( WAF1/CIP1 )