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ANGPT2 — GPI

Text-mined interactions from Literome

Jaimes et al., Kidney Int 2005 : In mesangial cells, Ang II significantly increased mesangial cell PGE ( 2 ) ( 200 % ) and PGI ( 2 ) ( 100 % ) production as well as COX-2 mRNA that was prevented by the angiotensin type 1 (AT1) receptor blocker irbesartan and the COX-2 inhibitor NS-398
Furuya et al., FASEB J 2013 (Hypertension...) : Interestingly, SphK1-knockout mice inhibited prostaglandin E ( 2 ) ( PGE ( 2 ) ) but not PGI ( 2 ) production in response to Ang II , whereas celecoxib blocked both PGE ( 2 ) and PGI ( 2 ) production
Nakagawa et al., J Cardiovasc Pharmacol 1987 : In rat aortic rings, ANG I, ANG II , and BK enhanced whereas captopril ( 10 ( -3 ) M ) attenuated PGI2 generation
Miyamori et al., Clin Exp Hypertens A 1985 (Body Weight...) : PGI2 generation which was measured by 6-keto-PGF1 alpha output in the perfusate was significantly reduced in DX treated rats at prehypertensive stage both under the basal conditions and in response to angiotensin (ANG) II , whereas in DOCA group rats, vascular PGI2 production was not impaired
Spatz et al., Am J Physiol 1994 : ANG II maximally stimulated PGI2 secretion during the 4- to 8-h interval, whereas AVP did not stimulate PGI2 secretion
Camilión de Hurtado et al., Circ Res 1998 : Under this condition, Ang II increased pHi from 7.05+/-0.05 to 7.22+/-0.05 ( P < .05 )