Hopkins et al., Circulation 2002
(Hypertension) :
A clear association between AGT genotype and response to infused Ang II was demonstrated for both the renal vasculature and the adrenal, consistent with the hypothesis that the AGT -6A genotype results in increased tissue expression of angiotensinogen and Ang II
Gonzalez-Villalobos et al., American journal of physiology. Renal physiology 2010
(Disease Models, Animal...) :
When compared with controls ( 1.00 ), AGT protein ( by WB ) was increased by ANG II ( 1.29 +/- 0.13, P < 0.05 ), and this was not prevented by ACEi ( ACEi + ANG II, 1.31 +/- 0.14, P < 0.05 )