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ADCYAP1 — TTF1

Text-mined interactions from Literome

Kim et al., J Biol Chem 2002 : Based on the similarity of synthesis sites between PACAP and TTF-1 and, moreover, on the presence of conserved core TTF-1 binding motifs in the 5'-flanking region of the PACAP gene, we sought to uncover a regulatory role of TTF-1 in PACAP gene transcription ... In the C6 glioma cell-line, TTF-1 activates the PACAP promoter in a dose dependent manner ... Intracerebroventricular administration of an antisense TTF-1 oligodeoxynucleotide significantly decreased the PACAP mRNA level as well as TTF-1 protein content in the rat hypothalamus, suggesting that TTF-1 also regulates PACAP transcription in vivo
Son et al., Mol Cells 2007 : We previously showed that thyroid transcription factor 1 ( TTF-1 ) , a homeodomain containing transcription factor, specifically regulates PACAP gene expression in the rat hypothalamus