Gene interactions and pathways from curated databases and text-mining

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FBXO32 — IRF6

Text-mined interactions from Literome

Dehoux et al., FEBS Lett 2003 (Body Weight) : LPS ( 750 microg/100 g body weight ) induces MafBx and Murf mRNA ( respectively, 23-fold and 33-fold after 12 h ; P < 0.001 ) ... In summary, MafBx and Murf mRNA are up-regulated in response to LPS and might play a role in the muscle proteolysis observed
Jin et al., J Cell Biochem 2007 (Muscular Atrophy) : Daily intraperitoneal ( i.p. ) injection of curcumin ( 10-60 micro g/kg ) for 4 days inhibited, in a dose dependent manner, the LPS stimulated ( 1 mg/kg, i.p. ) increase of atrogin-1/MAFbx expression in gastrocnemius and extensor digitorum longus (EDL) muscles, resulting in the attenuation of muscle protein loss
Crossland et al., J Physiol 2010 (Disease Models, Animal...) : However, Dex did not prevent the LPS mediated increase in muscle atrophy F-box (MAFbx) and muscle RING finger 1 (MuRF1) mRNA expression, but did significantly reduce the LPS mediated increase in cathepsin-L mRNA expression and enzyme activity by 43 % ( P < 0.001 ) and 53 % ( P < 0.05 ), respectively
Martin et al., J Physiol Pharmacol 2012 : Both types of meloxicam treatment blocked LPS induced increase in atrogin-1