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ELK1 — EPHB2

Text-mined interactions from Literome

Cruzalegui et al., Oncogene 1999 : ERK activation induces phosphorylation of Elk-1 at multiple S/T-P motifs to high stoichiometry
Goetze et al., J Cardiovasc Pharmacol 2000 : We used GAL-Elk-1 expression plasmids to detect ERK dependent activation of Elk-1
Kontaridis et al., Mol Cell Biol 2002 : Both the catalytic activity and, to a much lesser extent, the Grb2 binding-tyrosyl phosphorylation sites of SHP-2 are required for maximal FGF-2 induced Erk activity and Elk-1 transactivation ... The constitutively active mutant of SHP-2 induces hyper-tyrosyl phosphorylation of FRS-2 alpha but fails to stimulate or potentiate either FGF-2 induced Erk activation or Elk-1 transactivation
Gallo et al., Oncogene 2002 : We show that Menin inhibits ERK dependent phosphorylation and activation of both JunD and the Ets-domain transcription factor Elk-1
Coogan et al., J Neurosci 2003 (MAP Kinase Signaling System) : Light pulses during the subjective night rapidly, but transiently, induce P-ERK , whereas P-Elk-1 is also induced, albeit with a slower time course
Vlotides et al., Mol Endocrinol 2006 (Pituitary Neoplasms) : EGF induced EGFR and ERK1/2 phosphorylation was followed by rapid MAPK kinase/ERK kinase dependent activation of Elk-1 and c-Fos
Chen et al., Bioorg Med Chem Lett 2006 : Of the 13 compounds tested, 4 compounds strongly inhibited ERK mediated phosphorylation of ribosomal S6 kinase-1 (Rsk-1) and/or the transcription factor Elk-1 and inhibited the proliferation of HeLa cervical carcinoma cells with IC ( 50 ) values in the 2-10 microM range
Lavaur et al., J Neurosci 2007 : In this study we show that the excitatory neurotransmitter, glutamate, induces an ERK dependent Elk-1 activation and nuclear relocalization
Kim et al., Cancer Biol Ther 2008 (MAP Kinase Signaling System) : Kaempferol was demonstrated to induce sustained ERK activation concomitantly with MEK1 and ELK1 activation, and this kaempferol induced apoptosis was suppressed by treatment with PD98059, the overexpression of a kinase-inactive ERK mutant, or ERK siRNA
Chuang et al., FEBS Lett 1994 : We also show that overexpression of ERK2 , encoding p42mapk, activates Myc, but not Elk-1
Whitmarsh et al., Mol Cell Biol 1997 : The ERK , JNK, and p38 groups of mitogen activated protein ( MAP ) kinases phosphorylate and activate Elk-1 in response to a variety of extracellular stimuli