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RGS16 — TNF
Text-mined interactions from Literome
Fong et al., Biochem J 2000
(Calcium Signaling) :
Furthermore, mobilization of calcium by A23187 and thapsigargin blocked the
TNFalpha mediated induction of
RGS16 , which was reversed by EGTA and by the immunosuppressants FK506 and cyclosporin A, suggesting that the calcineurin/NF-AT ( nuclear factor of activated T cells ) pathway may repress the up-regulation process
Patten et al., Naunyn Schmiedebergs Arch Pharmacol 2003
:
IL-1beta ( 1.75-fold ) and
TNFalpha ( 1.62-fold ) but not IL-6 and IFNgamma
induced RGS16 protein expression ... Interestingly, both, the IL-1beta- and TNFalpha-effect could be blocked by IL-1ra, indicating that also the
TNFalpha induced
RGS16 expression is mediated by IL-1