Gene interactions and pathways from curated databases and text-mining

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CDK4 — TNF

Text-mined interactions from Literome

Gaiotti et al., Mol Carcinog 2000 : Tumor necrosis factor-alpha promotes human papillomavirus ( HPV ) E6/E7 RNA expression and cyclin dependent kinase activity in HPV immortalized keratinocytes by a ras dependent pathway
Lee et al., Immunopharmacol Immunotoxicol 2012 : TNF-a induced the expression of CDK2/CDK4 , and reduced the expression of p21 ( waf1/cip1 ) /p27 ( kip1 )