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SLPI — TGFB1

Text-mined interactions from Literome

Sano et al., Kekkaku 1999 : In this study, we examined the effects of SLPI on the production of a proinflammatory cytokine, TNF-alpha, and immunosupressive cytokines, IL-10 and transforming growth factor-beta ( TGF-beta ) by macrophages ( M phi s ), in response to lipopolysaccharide (LPS) mediated stimulation and M. avium complex ( MAC ) infection, using recombinant half sized SLPI ( 1/2 SLPI ) consisting of C-terminal domain ( Arg55-Ala107 ) of intact SLPI
Jaumann et al., Eur Respir J 2000 (Bronchiolitis...) : The authors analysed the effects of TGF-beta1 on gene expression and protein release of SLPI by cultured human bronchial epithelial ( BEAS-2B ) cells
Spinella-Jaegle et al., Bone 2001 : In contrast, TGF-beta1 was not only unable to induce these markers, but it dramatically inhibited BMP-2 mediated OC gene expression and ALP activity
Liegibel et al., Exp Clin Endocrinol Diabetes 2004 : TGFbeta1 + 2 neutralising antibodies or the presence of indomethacine inhibited the mitogenic effect of fluid shear and reduced ALP activity to its control level
Wang et al., J Huazhong Univ Sci Technolog Med Sci 2005 : The exogenous TGFbeta1 induced a dose dependent decrease in cell proliferation and a dose dependent increase in ALP activity, which plateaued at 5 ng/ml. Smad2 and Smad3 proteins were detected only in the cytoplasm in the absence of TGFbeta1, and TGFbeta1, could stimulate the translocation of them from the cytoplasm to the nucleus
Katagiri et al., Biochem Biophys Res Commun 1990 : Dexamethasone, 1 alpha, 25-dihydroxyvitamin D3, transforming growth factor-beta 1 and insulin-like growth factor-I did not stimulate ALP activity
Nagano et al., J Periodontol 2006 : Fraction 3 ( Fr.3 ) and a transforming growth factor-beta 1 ( TGF-beta1 ) control reduced alkaline phosphatase (ALP) activity in ST2 but enhanced ALP activity in HPDL cells
Luo et al., Arch Med Res 2008 (Pulmonary Disease, Chronic Obstructive) : Expression of SLPI in NHBE cells was inhibited by TGFbeta(1) both at the mRNA level and the protein level ... Decreased expression of SLPI in the COPD rat model may be mainly caused by the increased expression of TGFbeta(1) , and this process is probably related to the activation of Smads signal pathway
Katagiri et al., J Cell Biol 1994 : TGF-beta 1 potentiated the inhibitory effect of BMP-2 on myotube formation, whereas TGF-beta 1 reduced ALP activity and osteocalcin production induced by BMP-2 in C2C12 cells
Duvos et al., In Vitro Cell Dev Biol Anim 1997 (Bone Resorption) : TGF-beta 1 ( transforming growth factor beta ) and BMP-2 had no significant effect on calcium metabolism ; however, ALP activity was inhibited by TGF-beta 1 and induced dose dependently by BMP-2