Gene interactions and pathways from curated databases and text-mining

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PDCD5 — TGFB1

Text-mined interactions from Literome

Mazars et al., Oncogene 2000 : The transforming growth factor beta ( TGF-beta ) plays an important role in constraining cellular proliferation, but it is also a potent inducer of programmed cell death or apoptosis
Ottaviani et al., Prog Mol Subcell Biol 2004 : PDGF-AB and TGF-beta1 partially inhibit the induced programmed cell death in an insect cell line, and the survival effect is mediated by the activation of phosphatidylinositol 3-kinase, PKA and PKC
de Luján Alvarez et al., Hepatology 2004 (Liver Neoplasms, Experimental...) : The aim of this study was to determine if transforming growth factor beta1 ( TGF-beta1 ) was involved in the programmed cell death on the foci
Quiroga et al., Biochem Pharmacol 2007 (Precancerous Conditions) : TGF-beta(1) , in turn, reduces hepatocytes antioxidant defenses and induces programmed cell death
Quiroga et al., Growth Factors 2009 (Liver Neoplasms...) : This TGF-beta(1) , alters antioxidant defences and induces programmed cell death
Sookoian et al., Atherosclerosis 2011 (Anoxia...) : Systems biology analysis revealed highly scored pathways involved in the regulation of programmed cell death , angiogenesis, and immune system, in which TGFB1 was mostly involved
Sachsenmeier et al., J Biol Chem 1996 : We have investigated the role of transforming growth factor-beta 1 ( TGF-beta 1 ) in suspension induced programmed cell death of cultured human keratinocytes
Tanaka et al., Cancer Res 1996 (Carcinoma, Hepatocellular...) : Although parental Hep3B cells were sensitive to apoptosis, the Hep3B-IRS-I transfected cells acquired resistance to TGF-beta1 induced programmed cell death
Maccarrone et al., Eur J Biochem 1996 (Leukemia, Erythroblastic, Acute) : Membrane modifications in human erythroleukemia K562 cells during induction of programmed cell death by transforming growth factor beta 1 or cisplatin
Taetle et al., Clin Cancer Res 1996 (Multiple Myeloma) : Using previously studied cell line models, flow cytometry detected programmed cell death induced by transforming growth factor beta1 in leukemia cells and by anti-growth factor receptor antibody treatment of IL-6 dependent myeloma cells, treatments which caused only modest increases in the percentage of cells undergoing morphological apoptosis and increased internucleosomal DNA degradation