Gene interactions and pathways from curated databases and text-mining

◀ Back to PRKCD

HGF — PRKCD

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: PRKCD → HGF (decreases) Ma et al., Br J Cancer 2007*
    Evidence: In c-MET-overexpressing SCLC cell line NCI-H69, hepatocyte growth factor (HGF) dramatically induced c-MET phosphorylation at phosphoepitopes pY1230/1234/1235 (catalytic tyrosine kinase), pY1003 (juxtamembrane), and also of paxillin at pY31 (CRKL-binding site). We utilised a global proteomics phosphoantibody array approach to identify further c-MET/HGF signal transduction intermediates in SCLC. Strong HGF induction of specific phosphorylation sites in phosphoproteins involved in c-MET/HGF signal ...