Gene interactions and pathways from curated databases and text-mining

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CNTN2 — PCNA

Text-mined interactions from Literome

Kao et al., J Virol 1999 : Since Tax activates transcription of the PCNA promoter, we investigated whether this activity contributes to the reduction of NER ... Tax increased endogenous PCNA protein expression, and analysis of Tax mutant proteins demonstrated that the reduction in NER correlated with Tax transactivation of PCNA gene expression
Kao et al., Oncogene 2000 (Cell Transformation, Neoplastic) : Transient HTLV-1 Tax expression suppresses cellular nucleotide excision repair, and this effect correlates with Tax transactivation of the proliferating cell nuclear antigen promoter
Lemoine et al., AIDS Res Hum Retroviruses 2000 : We have previously demonstrated that Tax activates expression of the cellular gene, proliferating cell nuclear antigen ( PCNA ), and that Tax suppresses DNA repair
Kibler et al., J Virol 2001 (HTLV-I Infections) : Here, we show that Tax represses the TATA-less cyclin A promoter
Haller et al., Mol Cell Biol 2002 : Tax also increased the association of CDK4 with its positive cyclin regulatory subunit
Edwards et al., J Virol 2008 : Although it has been demonstrated that Tax transactivates the PCNA promoter, the mechanism of transcriptional activation is unknown
Ressler et al., J Virol 1997 (HTLV-I Infections) : Human T-cell leukemia virus type 1 Tax transactivates the human proliferating cell nuclear antigen promoter ... By testing a series of PCNA promoter deletion constructs, we have demonstrated that the PCNA promoter can be transactivated by Tax