Gene interactions and pathways from curated databases and text-mining

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AGO2 — MYLIP

Text-mined interactions from Literome

Verrier et al., Glia 2009 : Over-expression of miR-29a enhances the association of PMP22 RNA with Argonaute 2 , a protein involved in miRNA function, and reduces the steady-state levels of PMP22
Elcheva et al., Mol Cell 2009 : Argonaute2 interacts with the same region of betaTrCP1 mRNA in an miR-183 dependent manner ... Here we demonstrate that CRD-BP prevents degradation of betaTrCP1 mRNA by attenuating its miR-183 dependent interaction with Ago2
Tsai et al., Biochem J 2009 : Furthermore, the activity of mir346 does not require Ago-2 ( Argonaute 2 )
Kim et al., Aging Cell 2011 : Silencing of Ago2 in ATSCs significantly induces upregulation of miR10b and miR23b expression
Zhang et al., PloS one 2012 : Transfection assay revealed that both Ago1 and Ago2 synergistically induced miR-21 and miR-21* when the mir-21 plasmid was co-transfected with either
Shimakami et al., J Virol 2012 (Genomic Instability) : These 3 ' supplementary base pair interactions of miR-122 are functionally important and are required for Ago2 recruitment to HCV RNA by miR-122, miR-122 mediated stabilization of HCV RNA, and production of infectious virus
Zhang et al., J Biol Chem 2013 (Carcinoma, Hepatocellular...) : The up-regulation by miR-490-3p also required the participation of Ago2
Tattikota et al., Mol Cell Proteomics 2013 : In addition, the loss of Ago2 resulted in the increased expression of miR-375 target genes, including gephyrin and ywhaz
Conrad et al., PloS one 2013 (Carcinoma, Hepatocellular...) : Here, we show that Argonaute (Ago) 2 protein binds to the HCV 5'-UTR in a miR-122 dependent manner, whereas the HCV 3'-UTR does not bind Ago2
Bradrick et al., RNA 2013 : Similar to functional assays, we found that association of immobilized HCV internal ribosome entry site ( IRES ) RNA with endogenous Ago2 requires both miR-122 expression and intact miR-122 target sites in cis