Gene interactions and pathways from curated databases and text-mining

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IL6 — LDLR

Text-mined interactions from Literome

Gierens et al., Arterioscler Thromb Vasc Biol 2000 (Hypercholesterolemia) : Interleukin-6 stimulates LDL receptor gene expression via activation of sterol-responsive and Sp1 binding elements ... Our data indicate that IL-6 induces stimulation of the LDL-R gene, resulting in enhanced gene transcription and LDL-R activity
Liu et al., Cell Growth Differ 1993 (Carcinoma, Hepatocellular...) : Other similar cytokines were investigated, and, of these, only interleukin 1 could increase both Egr-1 and LDL receptor activity