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CYP1A1 — IL6
Text-mined interactions from Literome
Bleau et al., Eur J Pharmacol 2003
(Inflammation...) :
Interleukin-1beta,
interleukin-6 , tumour necrosis factor-alpha and interferon-gamma released by a viral infection and an aseptic inflammation
reduce CYP1A1 , 1A2 and 3A6 expression in rabbit hepatocytes
Abdel-Razzak et al., FEBS Lett 1995
:
We have investigated the
effects of interleukin (IL)-1 beta and
IL6 on expression and phenobarbital ( PB ) induction of ethoxyresorufin O-deethylase ( EROD ) and pentoxyresorufin O-deethylase ( PROD ) activities, as well as on mRNA levels of
cytochromes P450 (CYP) 1A , 2B, 2C, 2E and 3A, in rat hepatocytes in primary culture
Barker et al., J Biol Chem 1994
:
We have previously shown that the inflammatory mediator
interleukin-1 suppressed transcription of
CYP1A1 and CYP1A2 mRNAs ( Barker, C.W., Fagan, J.B., and Pasco, D.S. ( 1992 ) J. Biol. Chem. 267, 8050-8055 )
Calleja et al., Biochem Biophys Res Commun 1997
:
Differential
effects of interleukin-1 beta,
interleukin-2 , and interferon-gamma on the inducible expression of
CYP 1A1 and CYP 1A2 in cultured rabbit hepatocytes